Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

Study Counts

Type	Study_count
Total_Studies	1892
interventional	1680
Observational	193
Registry	19

Studies over Time

```

Interventional Trials

Intervention Type

intervention_type	Study_Count
Drug	961
Biological	123
Biological\|Drug	74
Drug\|Other	62
Drug\|Procedure	61
Biological\|Drug\|Procedure	44
Drug\|placebo	33
Biological\|Drug\|Procedure\|Radiation	31
Procedure	31
Drug\|Procedure\|Radiation	25
Other	24
Biological\|Drug\|Other	20
Drug\|Other\|Procedure\|Radiation	17
Device	13
Biological\|Other	12
Drug\|Other\|Procedure	11
Behavioral	10
Drug\|Radiation	10
Biological\|Drug\|Radiation	9
Biological\|Drug\|Other\|Procedure	8
Biological\|Drug\|Other\|Procedure\|Radiation	8
Biological\|Procedure	6
Combination Product	6
Drug\|Genetic	6
Dietary Supplement\|Drug	4
Drug\|Genetic\|Other\|Procedure	4
Other\|Procedure	4
Behavioral\|Drug	3
Biological\|Drug\|placebo	3
Biological\|placebo	3
Device\|Drug\|Procedure	3
Behavioral\|Drug\|Procedure	2
Behavioral\|Other	2
Biological\|Genetic\|Other	2
Biological\|Radiation	2
Device\|Drug\|Other	2
Device\|Other	2
Device\|Radiation	2
Diagnostic Test	2
Dietary Supplement	2
Drug\|Other\|Radiation	2
Drug\|placebo\|Procedure	2
Genetic	2
Behavioral\|Biological\|Drug	1
Behavioral\|Diagnostic Test\|Other	1
Behavioral\|Dietary Supplement\|Other\|Procedure	1
Behavioral\|Drug\|placebo	1
Biological\|Device\|Drug\|Procedure\|Radiation	1
Biological\|Device\|Drug\|Radiation	1
Biological\|Dietary Supplement\|Drug\|placebo	1
Biological\|Drug\|Genetic	1
Biological\|Drug\|Genetic\|Other\|Procedure	1
Biological\|Drug\|Genetic\|Procedure\|Radiation	1
Biological\|Drug\|Other\|placebo	1
Biological\|Other\|Procedure	1
Combination Product\|Drug	1
Device\|Drug	1
Device\|Other\|Procedure	1
Device\|Procedure	1
Diagnostic Test\|Drug\|Other	1
Dietary Supplement\|Other\|placebo	1
Dietary Supplement\|placebo	1
Drug\|Genetic\|Other	1
Drug\|Genetic\|Procedure	1
Drug\|Genetic\|Procedure\|Radiation	1
Drug\|Other\|placebo	1
Drug\|Other\|placebo\|Procedure	1
Genetic\|Radiation	1
Other\|Radiation	1
Radiation	1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Weekly studies for each intervention

Studies by Country

Country	Study_Count
United States	950
NA	65
China	64
France	41
Italy	31
United States\|Canada	31
Germany	29
Canada	28
Spain	26
Japan	24
United Kingdom	23
Denmark	13
Korea, Republic of	13
Switzerland	9
Netherlands	8
United States\|Italy	8
Australia	7
United States\|Germany\|Italy	6
Israel	5
Taiwan	5
United States\|Australia	5
Austria	4
Poland	4
United States\|Puerto Rico	4
Austria\|Germany	3
Belgium	3
Belgium\|France	3
Denmark\|Norway\|Sweden	3
Greece	3
India	3
Norway	3
Singapore	3
United States\|France	3
United States\|Israel	3
Austria\|Czech Republic	2
Brazil	2
China\|Taiwan	2
Finland	2
Hong Kong\|Korea, Republic of\|Singapore\|Taiwan	2
Iceland	2
Ireland	2
Mexico	2
Russian Federation	2
Sweden	2
United States\|Australia\|Canada	2
United States\|Australia\|France	2
United States\|Austria\|Belgium\|Canada\|France\|Germany\|Ireland\|Israel\|Italy\|Netherlands\|Spain\|Sweden\|United Kingdom	2
United States\|Denmark	2
United States\|Denmark\|Germany	2
United States\|France\|Spain	2
United States\|Korea, Republic of	2
United States\|United Kingdom	2
Australia\|Austria\|Belarus\|Belgium\|Czech Republic\|Denmark\|France\|Georgia\|Germany\|Greece\|Ireland\|Israel\|Italy\|Netherlands\|Poland\|Russian Federation\|Spain\|Sweden\|Switzerland\|Turkey\|Ukraine\|United Kingdom	1
Australia\|Austria\|Belgium\|France\|Germany\|Greece\|Ireland\|Israel\|Italy\|Poland\|Spain\|Sweden\|Switzerland\|Ukraine\|United Kingdom	1
Australia\|Austria\|Ireland\|Spain\|United Kingdom	1
Australia\|Belgium\|Canada\|Czechia\|Denmark\|France\|Germany\|Greece\|Italy\|Netherlands\|Russian Federation\|Spain\|Sweden\|Switzerland\|United Kingdom	1
Australia\|Belgium\|Czechia\|Denmark\|France\|Greece\|Italy\|Netherlands\|Norway\|Poland\|Spain\|Switzerland\|Turkey	1
Australia\|China\|Korea, Republic of	1
Australia\|Denmark\|Norway	1
Australia\|France\|Germany\|Hungary\|Korea, Republic of\|Poland\|Singapore\|United Kingdom	1
Australia\|France\|Spain\|United Kingdom	1
Australia\|United States\|Belgium\|Canada\|Czechia\|Denmark\|Finland\|France\|Germany\|Greece\|Hungary\|Italy\|Japan\|New Zealand\|Norway\|Poland\|Romania\|Spain\|Sweden\|United Kingdom	1
Austria\|Belgium\|Denmark\|Estonia\|Finland\|France\|Germany\|Greece\|Ireland\|Italy\|Netherlands\|Norway\|Poland\|Portugal\|Slovakia\|Spain\|Sweden\|Switzerland\|Turkey\|United Kingdom	1
Austria\|Belgium\|France\|Germany\|Greece\|Luxembourg\|Portugal\|Spain	1
Austria\|Czech Republic\|Denmark\|Germany\|Greece\|Sweden\|Turkey\|United Kingdom	1
Austria\|Czechia\|Denmark\|Germany\|Italy\|Poland	1
Austria\|Czechia\|Germany	1
Austria\|France\|Germany\|Greece\|Italy\|Netherlands\|Spain\|United Kingdom	1
Austria\|France\|Germany\|Italy	1
Belarus	1
Belgium\|Estonia\|Lithuania\|Sweden	1
Belgium\|France\|Germany	1
Belgium\|France\|Greece\|Italy\|Spain	1
Belgium\|France\|Korea, Republic of\|Poland\|Spain	1
Belgium\|France\|Netherlands	1
Belgium\|France\|Switzerland	1
Belgium\|Israel\|Spain	1
Belgium\|United States\|Australia\|Austria\|Bulgaria\|Canada\|Czechia\|France\|Germany\|Greece\|Hungary\|India\|Israel\|Italy\|Poland\|Romania\|Russian Federation\|Serbia\|Spain\|Ukraine\|United Kingdom	1
Bulgaria\|Canada\|United States\|Australia\|Belgium\|Germany\|Hungary\|Ireland\|Israel\|Italy\|Poland\|Russian Federation\|Spain\|Switzerland\|Ukraine\|United Kingdom	1
Bulgaria\|Croatia\|Czechia\|France\|Germany\|Hungary\|India\|Italy\|Philippines\|Poland\|Portugal\|Serbia\|Slovakia\|South Africa\|United Kingdom	1
Canada\|United States\|Brazil\|Czechia\|France\|Germany\|Israel\|Japan\|Netherlands\|Poland\|Spain\|Turkey\|United Kingdom	1
China\|Hong Kong\|Korea, Republic of\|Malaysia\|Taiwan	1
Czech Republic\|United Kingdom	1
Czechia\|Denmark\|France\|Germany\|Netherlands\|Norway\|Poland\|Spain\|Sweden	1
Czechia\|Germany\|Greece\|Italy\|Spain\|Turkey	1
Czechia\|Greece\|Ireland\|Italy	1
Czechia\|Poland	1
Denmark\|Finland\|Iceland\|Norway\|Sweden	1
Denmark\|Finland\|Lithuania\|Norway\|Sweden	1
Denmark\|Germany\|Belgium\|Czechia\|Greece\|Italy\|Netherlands\|Serbia\|Spain\|Turkey	1
Denmark\|Germany\|Ireland\|United Kingdom	1
Finland\|Lithuania\|Norway\|Sweden	1
Finland\|Sweden	1
France\|Germany	1
France\|Germany\|Italy\|Spain	1
France\|Italy	1
France\|Spain	1
France\|United Kingdom	1
France\|United States\|Australia\|Austria\|Belgium\|Bulgaria\|Canada\|Czechia\|Greece\|Hungary\|Japan\|Korea, Republic of\|Poland\|Romania\|Russian Federation\|Spain\|Taiwan\|Turkey\|United Kingdom	1
Germany\|Greece	1
Germany\|Israel\|Italy	1
Germany\|Italy	1
Germany\|Italy\|Spain\|Sweden	1
Germany\|Netherlands\|United Kingdom	1
Greece\|Italy\|Netherlands	1
Greece\|Italy\|Turkey	1
Greece\|United States\|Australia\|Austria\|Belgium\|Canada\|Czechia\|Germany\|Hungary\|Ireland\|Israel\|Italy\|Poland\|Puerto Rico\|Romania\|Russian Federation\|Spain\|Switzerland\|Turkey\|United Kingdom	1
Hong Kong\|Japan\|Korea, Republic of\|Singapore\|Taiwan	1
Hong Kong\|Korea, Republic of\|Singapore	1
India\|Korea, Republic of\|Singapore	1
Iraq	1
Ireland\|United Kingdom	1
Israel\|Italy\|Poland\|South Africa\|United Kingdom	1
Italy\|Netherlands	1
Italy\|Switzerland	1
Korea, Republic of\|United States\|Austria\|Belgium\|Czechia\|Denmark\|Estonia\|France\|Greece\|Hungary\|Israel\|Italy\|Lithuania\|Netherlands\|Norway\|Poland\|Romania\|Russian Federation\|Spain\|Taiwan\|United Kingdom	1
Netherlands\|United Kingdom	1
Poland\|Serbia\|France\|Germany\|Greece\|Hungary\|Lithuania\|Spain\|Turkey\|United Kingdom	1
Portugal\|Singapore\|United States\|Argentina\|Australia\|Austria\|Belgium\|Brazil\|Canada\|Colombia\|Czechia\|Denmark\|France\|Germany\|Greece\|Hungary\|Israel\|Italy\|Japan\|Korea, Republic of\|Mexico\|Netherlands\|Norway\|Poland\|South Africa\|Spain\|Sweden\|Switzerland\|Taiwan\|Thailand\|Turkey\|Ukraine\|United Kingdom	1
Russian Federation\|Ukraine	1
Saudi Arabia	1
Slovakia\|Spain\|Sweden\|United Kingdom\|Serbia\|Australia\|Austria\|Belgium\|Czechia\|France\|Germany\|Greece\|Hungary\|Israel\|Italy\|Korea, Republic of\|New Zealand\|Poland\|Russian Federation	1
South Africa\|United States\|Argentina\|Australia\|Austria\|Belgium\|Canada\|Czech Republic\|France\|Israel\|Netherlands\|Poland\|Portugal\|Russian Federation\|Singapore\|Spain\|United Kingdom	1
Spain\|France\|Germany\|Italy\|Netherlands\|Sweden\|United Kingdom	1
Spain\|Turkey\|Ukraine\|United States\|Argentina\|Australia\|Belgium\|Brazil\|Bulgaria\|Croatia\|Czechia\|Georgia\|Germany\|Greece\|Hungary\|Japan\|Korea, Republic of\|North Macedonia\|Poland\|Portugal\|Romania\|Russian Federation\|Serbia\|United Kingdom	1
Sweden\|Spain\|United States\|Argentina\|Australia\|Belgium\|Brazil\|Canada\|Czechia\|Denmark\|France\|Germany\|Greece\|Hungary\|Israel\|Italy\|Japan\|Mexico\|Netherlands\|Norway\|Poland\|Russian Federation\|Turkey\|United Kingdom	1
Sweden\|Turkey\|Portugal\|Belgium\|Finland\|France\|Germany\|Israel\|Netherlands\|Norway\|Poland	1
Taiwan\|United Kingdom\|United States\|Australia\|Austria\|Belgium\|Czechia\|France\|Germany\|Greece\|Ireland\|Italy\|Korea, Republic of\|Netherlands\|New Zealand\|Poland\|Portugal\|Puerto Rico\|Spain	1
Tunisia	1
Turkey	1
United States\|Argentina	1
United States\|Argentina\|Australia\|Austria\|Belgium\|Brazil\|Canada\|Chile\|China\|Colombia\|Croatia\|Czechia\|Denmark\|France\|Germany\|Greece\|Hungary\|Israel\|Italy\|Japan\|Korea, Republic of\|Mexico\|Poland\|Portugal\|Russian Federation\|Serbia\|Singapore\|South Africa\|Spain\|Sweden\|Switzerland\|Taiwan\|Thailand\|Turkey\|United Kingdom	1
United States\|Argentina\|Australia\|Austria\|Belgium\|Brazil\|Canada\|China\|Czechia\|Denmark\|Egypt\|Finland\|France\|Germany\|Greece\|Hong Kong\|Israel\|Italy\|Japan\|Korea, Republic of\|Lebanon\|Mexico\|Netherlands\|Norway\|Poland\|Russian Federation\|Singapore\|South Africa\|Spain\|Sweden\|Taiwan\|Thailand\|Turkey\|United Kingdom	1
United States\|Argentina\|Australia\|Austria\|Belgium\|Bulgaria\|Canada\|China\|Czechia\|Korea, Republic of\|France\|Germany\|Greece\|Hungary\|Israel\|Italy\|Japan\|Taiwan\|Mexico\|Netherlands\|New Zealand\|Poland\|Romania\|Russian Federation\|Singapore\|Spain\|Switzerland\|Turkey\|Ukraine\|United Kingdom	1
United States\|Argentina\|Mexico	1
United States\|Australia\|Austria\|Belgium\|Brazil\|Bulgaria\|Canada\|Czechia\|France\|Germany\|Greece\|Hungary\|Israel\|Italy\|Japan\|Korea, Republic of\|New Zealand\|Poland\|Romania\|Russian Federation\|Singapore\|Slovakia\|Spain\|Taiwan\|Thailand\|Ukraine\|United Kingdom	1
United States\|Australia\|Austria\|Belgium\|Canada\|China\|France\|Germany\|Greece\|Ireland\|Italy\|Korea, Republic of\|New Zealand\|Portugal\|Spain\|Sweden\|Switzerland\|Taiwan\|United Kingdom	1
United States\|Australia\|Austria\|Belgium\|Canada\|Czechia\|Denmark\|France\|Germany\|Greece\|Hungary\|Ireland\|Israel\|Italy\|Japan\|Poland\|Puerto Rico\|Romania\|Spain\|Switzerland\|Turkey\|United Kingdom	1
United States\|Australia\|Austria\|Belgium\|Canada\|Denmark\|France\|Germany\|Ireland\|Israel\|Netherlands\|Sweden\|United Kingdom	1
United States\|Australia\|Austria\|Bulgaria\|Canada\|Czechia\|France\|Germany\|Greece\|Hong Kong\|Hungary\|Ireland\|Italy\|Japan\|Korea, Republic of\|Lithuania\|Malaysia\|New Zealand\|Poland\|Portugal\|Russian Federation\|Singapore\|Slovakia\|Spain\|Switzerland\|Taiwan\|Turkey\|Ukraine\|United Kingdom	1
United States\|Australia\|Belgium\|Brazil\|Canada\|Czechia\|France\|Germany\|Greece\|Hungary\|Italy\|Korea, Republic of\|Lebanon\|Netherlands\|Norway\|Poland\|Portugal\|Russian Federation\|Spain\|Sweden\|Thailand\|Turkey	1
United States\|Australia\|Belgium\|Canada\|Czechia\|Denmark\|France\|Germany\|Greece\|Hungary\|Italy\|Japan\|Korea, Republic of\|New Zealand\|Norway\|Poland\|Portugal\|Russian Federation\|Slovakia\|Spain\|Sweden\|Taiwan\|Turkey\|United Kingdom	1
United States\|Australia\|Belgium\|Canada\|Czechia\|Denmark\|France\|Germany\|Greece\|Israel\|Italy\|Netherlands\|Norway\|Russian Federation\|Spain\|Sweden\|Turkey\|United Kingdom	1
United States\|Australia\|Belgium\|Canada\|Czechia\|Denmark\|France\|Germany\|Greece\|Italy\|Netherlands\|Russian Federation\|Spain\|Sweden\|Switzerland\|United Kingdom	1
United States\|Australia\|Belgium\|Canada\|Denmark\|France\|Germany\|Greece\|Israel\|Japan\|Korea, Republic of\|Netherlands\|Poland\|Russian Federation\|Spain\|Sweden\|Taiwan\|United Kingdom	1
United States\|Australia\|Belgium\|Canada\|Netherlands\|Spain	1
United States\|Australia\|Belgium\|China\|Czechia\|Denmark\|France\|Germany\|Greece\|Italy\|Japan\|Lithuania\|Mexico\|New Zealand\|Poland\|Portugal\|Russian Federation\|Spain\|Sweden\|Taiwan\|Turkey	1
United States\|Australia\|Belgium\|France\|Germany\|Greece\|Israel\|Korea, Republic of\|Spain\|Sweden\|United Kingdom	1
United States\|Australia\|Belgium\|France\|Spain	1
United States\|Australia\|Belgium\|Japan\|Switzerland	1
United States\|Australia\|Brazil\|Canada\|Czechia\|France\|Greece\|Hungary\|Italy\|Japan\|Korea, Republic of\|New Zealand\|Russian Federation\|Spain\|Turkey\|United Kingdom	1
United States\|Australia\|Brazil\|Canada\|Czechia\|France\|Greece\|Hungary\|Italy\|Spain	1
United States\|Australia\|Brazil\|Canada\|Czechia\|France\|Greece\|Israel\|Italy\|Japan\|Korea, Republic of\|Poland\|Russian Federation\|Spain\|Sweden\|Taiwan\|Ukraine\|United Kingdom	1
United States\|Australia\|Brazil\|Czechia\|Germany\|Hungary\|Korea, Republic of\|Mexico\|Netherlands\|Poland\|Russian Federation\|Spain\|Sweden\|Turkey\|Ukraine	1
United States\|Australia\|Canada\|China\|Czechia\|France\|Germany\|Greece\|Israel\|Italy\|Japan\|Korea, Republic of\|Russian Federation\|Singapore\|Spain\|Sweden\|Turkey\|United Kingdom	1
United States\|Australia\|Canada\|Czechia\|France\|Germany\|Israel\|Netherlands\|Russian Federation\|Turkey\|United Kingdom	1
United States\|Australia\|Canada\|Denmark\|France\|Germany	1
United States\|Australia\|Canada\|France\|Germany\|Greece\|Italy\|Japan\|Netherlands\|Poland\|Spain	1
United States\|Australia\|Canada\|France\|Germany\|Italy\|Korea, Republic of\|Spain	1
United States\|Australia\|Canada\|France\|Germany\|Italy\|Spain\|United Kingdom	1
United States\|Australia\|Canada\|France\|Germany\|Netherlands\|Turkey	1
United States\|Australia\|Canada\|Germany\|Italy\|Spain	1
United States\|Australia\|Canada\|Germany\|Japan	1
United States\|Australia\|Canada\|India	1
United States\|Australia\|Canada\|Ireland\|Taiwan	1
United States\|Australia\|Canada\|Netherlands\|Spain\|Sweden	1
United States\|Australia\|France\|Germany\|Italy\|Japan\|Spain	1
United States\|Australia\|France\|Greece\|Italy\|Japan	1
United States\|Australia\|France\|India\|Israel\|Korea, Republic of\|Poland\|Romania\|Russian Federation\|Singapore\|Spain	1
United States\|Australia\|France\|Israel\|Japan\|Spain\|Taiwan	1
United States\|Australia\|France\|Poland	1
United States\|Australia\|France\|Spain	1
United States\|Australia\|France\|Spain\|United Kingdom	1
United States\|Australia\|Germany	1
United States\|Australia\|Germany\|Italy\|Singapore	1
United States\|Australia\|Germany\|Japan\|Netherlands	1
United States\|Australia\|Germany\|Singapore\|Spain	1
United States\|Australia\|Greece	1
United States\|Australia\|Greece\|Poland\|Sweden	1
United States\|Australia\|Hungary\|Puerto Rico\|Spain	1
United States\|Australia\|Israel\|Norway	1
United States\|Australia\|Korea, Republic of	1
United States\|Australia\|Spain	1
United States\|Australia\|United Kingdom	1
United States\|Austria\|Belgium\|Bulgaria\|Canada\|Czechia\|France\|Germany\|Greece\|Hungary\|Israel\|Italy\|Netherlands\|Poland\|Romania\|Russian Federation\|Serbia\|Spain\|Sweden\|United Kingdom	1
United States\|Austria\|Belgium\|France\|Germany\|Greece	1
United States\|Austria\|Canada\|Czechia\|Denmark\|Germany\|Greece\|Israel\|Italy\|Norway\|Portugal\|Puerto Rico\|Spain\|Sweden\|Switzerland	1
United States\|Austria\|Canada\|Denmark\|Finland\|France\|Germany\|Greece\|Ireland\|Israel\|Italy\|Japan\|Netherlands\|Norway\|Poland\|Portugal\|Puerto Rico\|Russian Federation\|Spain\|Sweden\|Turkey\|United Kingdom	1
United States\|Austria\|Greece\|Netherlands\|Spain\|Sweden	1
United States\|Belgium	1
United States\|Belgium\|Brazil\|Bulgaria\|Canada\|Czechia\|France\|Germany\|Greece\|Hungary\|Netherlands\|Poland\|Portugal\|Romania\|Russian Federation\|Slovakia\|Spain\|United Kingdom	1
United States\|Belgium\|Brazil\|Canada\|Denmark\|France\|Germany\|Greece\|Italy\|Netherlands\|Poland\|Russian Federation\|Spain	1
United States\|Belgium\|Canada\|China\|Greece\|Korea, Republic of\|Poland\|Singapore\|Spain\|Sweden	1
United States\|Belgium\|Canada\|Czech Republic\|Finland\|France\|Germany\|Greece\|Israel\|Slovakia\|Switzerland\|Turkey\|United Kingdom	1
United States\|Belgium\|Canada\|Denmark\|Germany\|Italy\|Spain\|Sweden\|United Kingdom	1
United States\|Belgium\|Canada\|France\|Germany\|Greece\|Spain\|United Kingdom	1
United States\|Belgium\|Canada\|France\|Germany\|Italy\|Japan\|Netherlands\|Norway\|Spain\|Sweden	1
United States\|Belgium\|Canada\|France\|Germany\|Italy\|Japan\|Spain	1
United States\|Belgium\|Canada\|France\|Korea, Republic of\|New Zealand\|Russian Federation	1
United States\|Belgium\|Denmark\|Sweden	1
United States\|Belgium\|France\|Germany\|Israel\|Netherlands\|Spain	1
United States\|Belgium\|France\|Greece\|Italy\|Poland	1
United States\|Belgium\|France\|Italy\|Spain	1
United States\|Belgium\|France\|Netherlands\|Spain\|Sweden	1
United States\|Belgium\|France\|Norway	1
United States\|Belgium\|Russian Federation	1
United States\|Brazil\|Canada\|France\|Germany\|Greece\|Italy\|Korea, Republic of\|Mexico\|Netherlands\|Poland\|Spain\|Taiwan\|Turkey\|United Kingdom	1
United States\|Brazil\|Czechia\|France\|Germany\|Israel\|Japan\|Spain\|United Kingdom	1
United States\|Bulgaria\|Czechia\|France\|Germany\|Greece\|Japan\|Netherlands\|Romania\|Russian Federation\|Spain\|Sweden\|Turkey	1
United States\|Canada\|Czechia\|Denmark\|France\|Germany\|Greece\|Italy\|Spain	1
United States\|Canada\|Czechia\|Spain\|United Kingdom	1
United States\|Canada\|Denmark\|Finland\|Germany\|Italy\|Netherlands\|Spain	1
United States\|Canada\|Denmark\|Finland\|Spain\|United Kingdom	1
United States\|Canada\|France\|Germany\|Italy\|Japan\|Netherlands\|Spain\|United Kingdom	1
United States\|Canada\|France\|Germany\|Italy\|Netherlands\|Spain	1
United States\|Canada\|France\|Italy\|Poland	1
United States\|Canada\|France\|Italy\|Spain	1
United States\|Canada\|Germany	1
United States\|Canada\|Germany\|Netherlands\|Spain	1
United States\|Canada\|Germany\|Spain	1
United States\|Canada\|Greece\|Italy	1
United States\|Canada\|Israel\|Italy\|Russian Federation	1
United States\|Canada\|Italy	1
United States\|Canada\|Japan\|Puerto Rico	1
United States\|Canada\|Spain	1
United States\|Canada\|United Kingdom	1
United States\|China\|France\|Germany\|Spain\|United Kingdom	1
United States\|Czech Republic\|Germany	1
United States\|Czechia\|France	1
United States\|Czechia\|France\|Greece\|Netherlands\|Poland	1
United States\|Czechia\|France\|Spain	1
United States\|Denmark\|France\|Netherlands\|Spain\|Sweden	1
United States\|Denmark\|France\|Netherlands\|United Kingdom	1
United States\|Denmark\|Italy\|Netherlands\|Sweden	1
United States\|Denmark\|Netherlands\|Sweden	1
United States\|Denmark\|Norway\|United Kingdom	1
United States\|France\|Germany	1
United States\|France\|Germany\|Greece\|Spain	1
United States\|France\|Germany\|Spain\|United Kingdom	1
United States\|France\|Italy\|Netherlands\|Spain\|Switzerland	1
United States\|France\|Italy\|Spain	1
United States\|France\|Korea, Republic of	1
United States\|France\|Netherlands	1
United States\|France\|Spain\|United Kingdom	1
United States\|Germany	1
United States\|Germany\|Italy\|Spain	1
United States\|Germany\|Singapore\|Spain	1
United States\|Germany\|Spain	1
United States\|Germany\|Spain\|Sweden	1
United States\|Greece\|Italy\|Poland	1
United States\|Ireland\|Puerto Rico	1
United States\|Japan	1
United States\|Netherlands	1
United States\|Netherlands\|Spain	1
United States\|Peru\|South Africa	1
United States\|Philippines\|United Kingdom	1
United States\|Poland	1
United States\|Puerto Rico\|Saudi Arabia	1
United States\|Puerto Rico\|South Africa	1
United States\|Singapore	1
United States\|Spain	1
United States\|Spain\|United Kingdom	1
United States\|Sweden	1

Sites per Study

Site_count	Study_Count
1	823
2	118
3	70
4	55
5	68
6	41
7	37
8	40
9	40
10	37
11	28
12	20
13	22
14	17
15	6
16	13
17	12
18	9
19	12
20	9
21	7
22	8
23	5
24	8
25	2
26	6
27	4
28	6
29	2
30	7
31	5
32	3
33	3
34	5
35	4
36	2
37	3
38	3
39	3
40	5
41	1
42	2
43	2
44	1
45	1
46	2
47	1
48	1
49	4
54	2
55	2
56	1
57	2
58	1
59	2
60	1
61	1
63	2
64	3
68	4
69	2
70	2
71	1
73	1
74	2
76	1
77	3
78	1
79	1
80	1
82	1
84	1
86	2
91	2
92	1
93	1
94	1
95	1
98	1
99	1
105	1
107	2
109	1
110	1
111	2
112	1
114	1
115	1
117	1
121	1
127	1
128	1
138	1
140	2
141	1
145	1
147	1
148	1
157	1
163	1
165	2
178	1
198	1
210	1
213	1
215	1
224	1
235	1
241	1
248	1
278	1
288	1
309	1
326	1
336	1
393	1
417	1
485	1
498	1
504	1
505	1
506	1
613	1
920	1
1328	1

Phase

Phase	Study_Count
Phase 2	663
Phase 1	398
Phase 1/Phase 2	232
Phase 3	219
N/A	112
Phase 4	25
Early Phase 1	18
Phase 2/Phase 3	13

Number of Arms

Number_of_Arms	Count_of_Studies
1	824
2	397
3	102
4	46
5	24
6	13
7	8
8	4
9	2
10	3
11	5
12	2
13	2
17	1
21	1
37	1
NA	245

Number of Updates

Count of Versions	Count of Studies
1	64
2	107
3	75
4	93
5	95
6	74
7	65
8	80
9	90
10	78
11	57
12	60
13	58
14	41
15	44
16	37
17	43
18	46
19	28
20	35
21	23
22	31
23	20
24	19
25	26
26	24
27	17
28	14
29	12
30	15
31	9
32	11
33	5
34	6
35	12
36	9
37	5
38	9
39	8
40	5
41	8
42	6
43	2
44	5
45	2
46	6
47	5
48	4
49	4
50	6
51	6
52	4
53	5
54	1
55	4
57	1
58	1
59	3
60	1
61	2
62	3
63	2
65	1
66	4
67	2
68	1
69	2
70	1
71	3
72	1
73	1
74	1
76	1
77	1
80	2
81	2
83	1
88	1
93	1
96	1
97	1
101	1
109	1
114	2
115	1
117	2
121	1
123	1
143	1
148	1
158	1
174	1
203	1
213	1
259	1
415	1
443	1
456	1
881	1
1004	1

Update History Change Type

Change Type	Count_of_Changes	Count_of_Studies	ratio
Study Status	28866	1616	17.862624
Contacts/Locations	12626	1486	8.496635
Arms	3196	1084	2.948339
Interventions	3196	1084	2.948339
Recruitment Status	3164	1450	2.182069
Study Design	2837	1238	2.291599
Eligibility	2682	1054	2.544592
Study Identification	2449	1006	2.434394
Study Description	2271	868	2.616359
Outcome Measures	2208	973	2.269270
Conditions	1979	647	3.058733
Sponsor/Collaborators	1916	969	1.977296
None (earliest Version on record)	1680	1680	1.000000
Oversight	1337	898	1.488864
More Information	893	255	3.501961
References	733	397	1.846348
Results	363	363	1.000000
IPDSharing	214	176	1.215909
Baseline Characteristics	174	126	1.380952
Reported Adverse Events	101	86	1.174419
Participant Flow	88	72	1.222222
Results Submission Events	83	83	1.000000
Documents	82	80	1.025000

Enrollment Metrics by Phase

Measure	Early.Phase.1	N.A	Phase.1	Phase.1.Phase.2	Phase.2	Phase.2.Phase.3	Phase.3	Phase.4
Min.	6.00000	2.0000	1.00000	3.00000	2.00000	4.0000	14.0000	18.0000
1st Qu.	11.25000	20.0000	18.00000	31.00000	30.00000	22.0000	180.0000	49.2500
Median	16.50000	50.0000	30.00000	50.00000	46.00000	86.0000	316.0000	111.5000
Mean	21.27778	811.4037	44.62304	69.26906	88.25359	139.2308	417.9187	135.4583
3rd Qu.	20.00000	100.0000	57.50000	80.00000	83.50000	169.0000	522.0000	164.7500
Max.	100.00000	80761.0000	335.00000	449.00000	6452.00000	400.0000	4420.0000	500.0000

Trial Group Type

group_type	Group_Count
Experimental	2156
Active Comparator	289
NA	245
Other	96
Placebo Comparator	44
No Intervention	32
Sham Comparator	5

Intervention Model

intervention_model	Study_Count
Single Group Assignment	987
Parallel Assignment	491
NA	113
Sequential Assignment	68
Crossover Assignment	16
Factorial Assignment	5

Primary Purpose

primary_purpose	Study_Count
Treatment	1494
Supportive Care	84
Prevention	33
Diagnostic	23
Other	15
NA	14
Basic Science	7
Screening	5
Health Services Research	4
Device Feasibility	1

Observational Studies

Studies by Country

Country	Study_Count
United States	70
NA	19
France	17
Italy	11
Korea, Republic of	8
Spain	8
Germany	7
Japan	7
Greece	4
United Kingdom	4
Denmark	3
Netherlands	3
Turkey	3
Austria	2
China	2
Norway	2
United States\|Canada	2
Argentina\|Brazil\|Chile\|Colombia\|Guatemala\|Mexico\|Panama	1
Austria\|Belgium\|Bulgaria\|Czechia\|France\|Greece\|Israel\|Italy\|Netherlands\|Norway\|Romania	1
Belgium	1
Brazil	1
Canada	1
Czech Republic	1
Germany\|Austria\|Belgium\|Czech Republic\|France\|Hungary\|Italy\|Poland\|Romania\|Spain\|Switzerland\|United Kingdom	1
Guadeloupe\|Martinique	1
Italy\|United Kingdom	1
Mexico	1
Russian Federation	1
Russian Federation\|Algeria\|Austria\|Croatia\|Denmark\|Estonia\|France\|Germany\|Greece\|Hungary\|Israel\|Latvia\|Lithuania\|Macedonia, The Former Yugoslav Republic of\|Poland\|Portugal\|Slovenia\|South Africa\|Spain\|Turkey\|Ukraine	1
Sweden	1
Switzerland	1
Taiwan	1
United States\|Belgium\|Brazil\|China\|Colombia\|France\|Germany\|Greece\|Israel\|Italy\|Mexico\|Spain\|Taiwan\|Turkey\|United Kingdom	1
United States\|Belgium\|France\|Germany\|Italy\|Netherlands\|Poland\|Russian Federation\|Spain\|United Kingdom	1
United States\|Canada\|France\|Germany\|Italy\|United Kingdom	1
United States\|Canada\|Spain	1
United States\|Mexico\|Saudi Arabia	1
United States\|Puerto Rico	1

Sites per Study

Site_count	Study_Count
1	120
2	10
3	4
4	1
5	2
6	4
7	2
8	1
9	4
10	3
13	2
15	1
16	1
20	6
21	1
22	1
23	1
24	1
25	1
27	2
28	1
29	1
30	1
35	1
38	1
39	1
40	1
44	2
65	1
69	1
73	1
81	1
94	1
112	1
120	1
126	1
137	2
138	1
144	1
161	1
207	1
253	1
453	1

Number of Updates

Count of Versions	Count of Studies
1	19
2	22
3	17
4	18
5	17
6	9
7	10
8	15
9	6
10	7
11	7
12	2
13	4
14	3
16	3
17	3
18	1
20	1
22	1
23	1
24	1
30	3
33	1
34	1
36	1
37	1
39	1
44	2
48	2
53	1
61	1
69	1
73	1
88	1
101	1
108	1
112	1
116	1
119	1
144	1
165	1
250	1
391	1

Update History Change Type

Change Type	Count_of_Changes	Count_of_Studies	ratio
Study Status	3149	174	18.097701
Contacts/Locations	1604	144	11.138889
Study Description	332	68	4.882353
Study Design	259	126	2.055556
Recruitment Status	213	134	1.589552
None (earliest Version on record)	193	193	1.000000
Eligibility	184	76	2.421053
Study Identification	135	79	1.708861
Sponsor/Collaborators	124	87	1.425287
Conditions	116	44	2.636364
Outcome Measures	111	73	1.520548
Groups	95	58	1.637931
Interventions	95	58	1.637931
Oversight	83	63	1.317460
References	60	36	1.666667
More Information	16	2	8.000000
IPDSharing	8	8	1.000000
Results	3	3	1.000000
Documents	2	2	1.000000
Baseline Characteristics	1	1	1.000000
Results Submission Events	1	1	1.000000

Enrollment Metrics

Measure	Observational
Min	7.000
1st Qu	60.500
Median	196.000
Mean	2105.749
3rd Qu	600.000
Max	99999.000

Observation Model

observational_model	Study_Count
Cohort	92
Case-Only	55
Other	19
NA	11
Case-Control	8
Case Control	6
Family-Based	2

Time Perspective

time_perspective	Study_Count
Prospective	144
Retrospective	27
NA	9
Cross-Sectional	6
Other	6
Longitudinal, Prospective	1

Registries

Studies by Country

Country	Study_Count
United States	7
France	2
Algeria\|Belgium\|France\|Lebanon	1
Argentina\|Brazil\|Colombia\|Mexico\|Panama	1
Austria\|Belgium\|Denmark\|France\|Germany\|Ireland\|Italy\|Netherlands\|Norway\|Spain\|Sweden\|United Kingdom	1
Belgium\|Denmark\|Germany\|Italy\|Norway\|Spain\|Sweden\|United Kingdom	1
China	1
Germany	1
Malaysia	1
NA	1
Portugal	1
Taiwan	1

Sites per Study

Site_count	Study_Count
1	11
2	1
7	1
12	1
20	1
33	1
75	1
118	1
135	1

Number of Updates

Count of Versions	Count of Studies
1	5
3	1
4	1
5	2
6	3
7	2
11	1
12	1
14	1
15	1
23	1

Update History Change Type

Change Type	Count_of_Changes	Count_of_Studies	ratio
Study Status	110	14	7.857143
Contacts/Locations	51	12	4.250000
None (earliest Version on record)	19	19	1.000000
Study Design	16	7	2.285714
References	12	5	2.400000
Study Identification	12	6	2.000000
Recruitment Status	9	7	1.285714
Conditions	8	4	2.000000
Eligibility	7	5	1.400000
Oversight	7	7	1.000000
Sponsor/Collaborators	7	5	1.400000
Outcome Measures	6	5	1.200000
Study Description	6	4	1.500000
Groups	3	3	1.000000
Interventions	3	3	1.000000
IPDSharing	3	2	1.500000

Enrollment Metrics

Measure	Registries
Min	100.00
1st Qu	350.00
Median	1000.00
Mean	54530.89
3rd Qu	2897.50
Max	999999.00

Registry Model

observational_model	Study_Count
Cohort	14
Other	3
Case-Only	1
Ecologic or Community	1

Time Perspective

time_perspective	Study_Count
Prospective	17
Cross-Sectional	1
Other	1

Follow-up

target_duration	Study_Count
10 Years	5
5 Years	4
1 Year	2
2 Years	2
1 Day	1
24 Months	1
3 Years	1
36 Months	1
8 Years	1
80 Years	1

intervention_type	Study_Count
Drug	961
Biological	123
Biological\|Drug	74
Drug\|Other	62
Drug\|Procedure	61
Biological\|Drug\|Procedure	44
Drug\|placebo	33
Biological\|Drug\|Procedure\|Radiation	31
Procedure	31
Drug\|Procedure\|Radiation	25
Other	24
Biological\|Drug\|Other	20
Drug\|Other\|Procedure\|Radiation	17
Device	13
Biological\|Other	12
Drug\|Other\|Procedure	11
Behavioral	10
Drug\|Radiation	10
Biological\|Drug\|Radiation	9
Biological\|Drug\|Other\|Procedure	8
Biological\|Drug\|Other\|Procedure\|Radiation	8
Biological\|Procedure	6
Combination Product	6
Drug\|Genetic	6
Dietary Supplement\|Drug	4
Drug\|Genetic\|Other\|Procedure	4
Other\|Procedure	4
Behavioral\|Drug	3
Biological\|Drug\|placebo	3
Biological\|placebo	3
Device\|Drug\|Procedure	3
Behavioral\|Drug\|Procedure	2
Behavioral\|Other	2
Biological\|Genetic\|Other	2
Biological\|Radiation	2
Device\|Drug\|Other	2
Device\|Other	2
Device\|Radiation	2
Diagnostic Test	2
Dietary Supplement	2
Drug\|Other\|Radiation	2
Drug\|placebo\|Procedure	2
Genetic	2
Behavioral\|Biological\|Drug	1
Behavioral\|Diagnostic Test\|Other	1
Behavioral\|Dietary Supplement\|Other\|Procedure	1
Behavioral\|Drug\|placebo	1
Biological\|Device\|Drug\|Procedure\|Radiation	1
Biological\|Device\|Drug\|Radiation	1
Biological\|Dietary Supplement\|Drug\|placebo	1
Biological\|Drug\|Genetic	1
Biological\|Drug\|Genetic\|Other\|Procedure	1
Biological\|Drug\|Genetic\|Procedure\|Radiation	1
Biological\|Drug\|Other\|placebo	1
Biological\|Other\|Procedure	1
Combination Product\|Drug	1
Device\|Drug	1
Device\|Other\|Procedure	1
Device\|Procedure	1
Diagnostic Test\|Drug\|Other	1
Dietary Supplement\|Other\|placebo	1
Dietary Supplement\|placebo	1
Drug\|Genetic\|Other	1
Drug\|Genetic\|Procedure	1
Drug\|Genetic\|Procedure\|Radiation	1
Drug\|Other\|placebo	1
Drug\|Other\|placebo\|Procedure	1
Genetic\|Radiation	1
Other\|Radiation	1
Radiation	1

Site_count	Study_Count
1	120
2	10
3	4
4	1
5	2
6	4
7	2
8	1
9	4
10	3
13	2
15	1
16	1
20	6
21	1
22	1
23	1
24	1
25	1
27	2
28	1
29	1
30	1
35	1
38	1
39	1
40	1
44	2
65	1
69	1
73	1
81	1
94	1
112	1
120	1
126	1
137	2
138	1
144	1
161	1
207	1
253	1
453	1

Count of Versions	Count of Studies
1	19
2	22
3	17
4	18
5	17
6	9
7	10
8	15
9	6
10	7
11	7
12	2
13	4
14	3
16	3
17	3
18	1
20	1
22	1
23	1
24	1
30	3
33	1
34	1
36	1
37	1
39	1
44	2
48	2
53	1
61	1
69	1
73	1
88	1
101	1
108	1
112	1
116	1
119	1
144	1
165	1
250	1
391	1

Site_count	Study_Count
1	120
2	10
3	4
4	1
5	2
6	4
7	2
8	1
9	4
10	3
13	2
15	1
16	1
20	6
21	1
22	1
23	1
24	1
25	1
27	2
28	1
29	1
30	1
35	1
38	1
39	1
40	1
44	2
65	1
69	1
73	1
81	1
94	1
112	1
120	1
126	1
137	2
138	1
144	1
161	1
207	1
253	1
453	1

Count of Versions	Count of Studies
1	19
2	22
3	17
4	18
5	17
6	9
7	10
8	15
9	6
10	7
11	7
12	2
13	4
14	3
16	3
17	3
18	1
20	1
22	1
23	1
24	1
30	3
33	1
34	1
36	1
37	1
39	1
44	2
48	2
53	1
61	1
69	1
73	1
88	1
101	1
108	1
112	1
116	1
119	1
144	1
165	1
250	1
391	1

multiple myeloma

Study Counts

Studies over Time

Interventional Trials

Intervention Type

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Studies by Country

Sites per Study

Phase

Number of Arms

Number of Updates

Update History Change Type

Enrollment Metrics by Phase

Trial Group Type

Intervention Model

Primary Purpose

Observational Studies

Studies by Country

Sites per Study

Number of Updates

Update History Change Type

Enrollment Metrics

Observation Model

Time Perspective

Registries

Studies by Country

Sites per Study

Number of Updates

Update History Change Type

Enrollment Metrics

Registry Model

Time Perspective

Follow-up

Site_count	Study_Count
1	120
2	10
3	4
4	1
5	2
6	4
7	2
8	1
9	4
10	3
13	2
15	1
16	1
20	6
21	1
22	1
23	1
24	1
25	1
27	2
28	1
29	1
30	1
35	1
38	1
39	1
40	1
44	2
65	1
69	1
73	1
81	1
94	1
112	1
120	1
126	1
137	2
138	1
144	1
161	1
207	1
253	1
453	1

Count of Versions	Count of Studies
1	19
2	22
3	17
4	18
5	17
6	9
7	10
8	15
9	6
10	7
11	7
12	2
13	4
14	3
16	3
17	3
18	1
20	1
22	1
23	1
24	1
30	3
33	1
34	1
36	1
37	1
39	1
44	2
48	2
53	1
61	1
69	1
73	1
88	1
101	1
108	1
112	1
116	1
119	1
144	1
165	1
250	1
391	1